Description

Azido-Dpeg4-Acid is a heterobifunctional polyethylene glycol (PEG) linker featuring an azide group and a carboxylic acid terminus. This compound is a critical reagent in bioconjugation and click chemistry, enabling the precise, high-yield coupling of biomolecules and other functional entities. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications such as antibody-drug conjugate (ADC) development, peptide modification, and polymer functionalization.

Application

• Bioconjugation reagent for linking biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC) click chemistry.
• Key intermediate in the synthesis of Antibody-Drug Conjugates (ADCs) and other targeted therapeutics.
• Functionalization of peptides, proteins, and oligonucleotides to introduce carboxylic acid handles for further modification.
• Surface modification and crosslinking agent for biomaterials and hydrogels.
• Building block for synthesizing PEGylated compounds to improve solubility and pharmacokinetics.
• Polymer chemistry for creating functionalized, water-soluble polymers with clickable azide groups.
• Development of diagnostic probes and imaging agents.
• Immobilization of ligands onto solid supports and sensor surfaces.

Basic Information

Product Name	Azido-Dpeg4-Acid
CAS No.	1056024-94-2
Molecular Formula	C15H27N3O7
Molecular Weight	361.39 g/mol
Synonyms	Azido-PEG4-acid; 15-Azido-4,7,10,13-tetraoxapentadecanoic acid; 3-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid; Azido-PEG4-CH2CH2COOH; N3-PEG4-COOH; Azido tetraethylene glycol acetic acid; Azido-PEG4-propionic acid; Azido-PEG4-acetic acid
EINECS	Contact for details

Quality Control

Our Azido-Dpeg4-Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive bioconjugation applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. Under these conditions, the product is typically stable for at least 24 months. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.