Description

tert-Butyl 2-(Azetidin-1-yl)acetate is a high-purity chemical building block featuring a protected carboxylic acid group and an azetidine moiety. This compound is of significant value in pharmaceutical research and development, serving as a versatile intermediate for constructing complex molecules. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Protease Inhibitor Synthesis: Used in the construction of molecules designed to inhibit specific proteolytic enzymes.
• Building Block for Bioactive Molecules: Employed to introduce the azetidine ring system, a valuable pharmacophore known to influence potency, selectivity, and metabolic stability.
• Process Chemistry & Scale-up: Suitable for use in optimizing synthetic routes from laboratory to pilot and commercial manufacturing scales.
• Chemical Biology & Probe Development: Utilized in the creation of chemical probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific compounds.

Basic Information

Product Name	tert-Butyl 2-(Azetidin-1-yl)acetate
CAS No.	1055268-73-9
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	1-Azetidineacetic acid, 1,1-dimethylethyl ester; 2-(Azetidin-1-yl)acetic acid tert-butyl ester; tert-Butyl azetidine-1-acetate; Azetidin-1-yl-acetic acid tert-butyl ester; (Azetidin-1-yl)acetic acid tert-butyl ester; tert-Butyl (azetidin-1-yl)acetate; 1055268-73-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(Azetidin-1-yl)acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring material for GLP (Good Laboratory Practice) and cGMP (current Good Manufacturing Practice) compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.