Description

2-Chloro-4-Fluoronicotinonitrile is a high-value, multi-functional chemical intermediate featuring a halogenated pyridine core. This compound matters for its role as a versatile building block in modern synthetic chemistry, enabling the construction of complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for creating functionalized ligands and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biological studies.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	2-Chloro-4-Fluoronicotinonitrile
CAS No.	1054552-27-0
Molecular Formula	C6H2ClFN2
Molecular Weight	156.55 g/mol
Synonyms	2-Chloro-4-fluoropyridine-3-carbonitrile; 3-Cyano-2-chloro-4-fluoropyridine; 4-Fluoro-2-chloronicotinonitrile; 2-Chloro-4-fluoro-3-pyridinecarbonitrile; 2-Chloro-4-fluoronicotinonitrile; 2-Chloro-4-fluoropyridine-3-carbonitrile; 1054552-27-0
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoronicotinonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.