Description

2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a protected boronic acid, offering enhanced stability and solubility for use in cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for constructing complex heterocyclic scaffolds. We supply this material with a focus on consistent purity and reliable global availability to support your R&D and production timelines.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing pyridine and bipyridine motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science: Precursor for organic electronic materials, including ligands for OLEDs and catalysts.
• Suzuki-Miyaura Cross-Coupling: A stable and versatile reagent for forming carbon-carbon bonds between aryl/heteroaryl groups.
• Chemical Research & Development: Serves as a versatile intermediate in academic and industrial research for exploring new chemical entities.
• Ligand Synthesis: Used to prepare complex ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1054483-78-1
Molecular Formula	C11H16BNO3
Molecular Weight	221.06 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol; 2-Pyridinol, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-hydroxypyridine; 2-Hydroxy-5-(pinacolatoboryl)pyridine; 5-Pinacolatoboryl-2-hydroxypyridine; 2-Pyridone Boronic Acid Pinacol Ester; 5-(Pinacolboron)pyridin-2-ol
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure it meets the high-purity standards required for sensitive applications like pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.