Description

Methyl (3-(Trifluoromethyl)Pyridin-2-Ylsulfanyl) Acetate is a high-value, specialized chemical intermediate featuring a pyridine core substituted with a trifluoromethyl group and a thioacetate ester moiety. This compound is critical for its role in facilitating the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, crop protection, and advanced materials sectors who require a reliable source of this specific building block for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethylpyridine unit enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis, especially in cross-coupling reactions critical for C-C and C-N bond formation.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers or components for OLEDs, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects.

Basic Information

Product Name	Methyl (3-(Trifluoromethyl)Pyridin-2-Ylsulfanyl) Acetate
CAS No.	1053660-04-0
Molecular Formula	C9H8F3NO2S
Molecular Weight	251.22 g/mol
Synonyms	Methyl 2-(((3-(trifluoromethyl)pyridin-2-yl)thio)acetate; 2-(((3-(Trifluoromethyl)-2-pyridinyl)thio)acetic Acid Methyl Ester; Acetic acid, 2-[[[3-(trifluoromethyl)-2-pyridinyl]thio]-, methyl ester; Methyl (3-trifluoromethylpyridin-2-ylthio)acetate; 2-(3-Trifluoromethyl-pyridin-2-ylsulfanyl)-acetic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl (3-(Trifluoromethyl)Pyridin-2-Ylsulfanyl) Acetate undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality assurance protocol includes identity confirmation, purity assay, and impurity profiling via techniques such as HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.