Description

n-Benzyl-6-Chloro-4-(Trifluoromethyl)-Pyridin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine core substituted with chloro, trifluoromethyl, and benzylamino functional groups. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel small-molecule drugs targeting various disease pathways.
• Agrochemical Research: Serves as a structural motif in the synthesis of new generation pesticides and herbicides, leveraging the stability of the trifluoromethyl group.
• Material Science: Used in the research and development of specialty chemicals and functional materials, including liquid crystals and organic semiconductors.
• Academic & Contract Research: Employed in university and CRO laboratories for method development, structure-activity relationship (SAR) studies, and chemical biology research.
• Custom Synthesis: A starting material for the custom synthesis of more complex, tailored molecules for specific client R&D projects.

Basic Information

Product Name	n-Benzyl-6-Chloro-4-(Trifluoromethyl)-Pyridin-2-Amine
CAS No.	1053659-65-6
Molecular Formula	C13H10ClF3N2
Molecular Weight	286.68 g/mol
Synonyms	6-Chloro-N-benzyl-4-(trifluoromethyl)pyridin-2-amine; 2-Pyridinamine, 6-chloro-N-(phenylmethyl)-4-(trifluoromethyl)-; N-Benzyl-6-chloro-4-trifluoromethylpyridin-2-amine; 1053659-65-6; 6-Chloro-4-(trifluoromethyl)-2-(benzylamino)pyridine
EINECS	Contact for details

Quality Control

Our n-Benzyl-6-Chloro-4-(Trifluoromethyl)-Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.