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4'-(5-Bromo-6-Chloro-4-(Trifluoromethyl)-Pyridin-2-Yl)Morpholine CAS NO 1053659-46-3
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CAS No.:1053659-46-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4'-(5-Bromo-6-Chloro-4-(Trifluoromethyl)-Pyridin-2-Yl)Morpholine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters because its unique halogenated and trifluoromethylated pyridine-morpholine structure offers significant potential for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in medicinal chemistry for drug discovery programs.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
- Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and halogen groups can enhance bioavailability and environmental stability.
- Material Science Precursor: Serves as a specialized monomer or ligand in the development of advanced functional materials, including organic semiconductors and metal-organic frameworks (MOFs).
- Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions in biochemical research.
- Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
Basic Information
| Product Name | 4'-(5-Bromo-6-Chloro-4-(Trifluoromethyl)-Pyridin-2-Yl)Morpholine |
| CAS No. | 1053659-46-3 |
| Molecular Formula | C10H9BrClF3N2O |
| Molecular Weight | 345.54 g/mol |
| Synonyms | 2-(5-Bromo-6-chloro-4-(trifluoromethyl)pyridin-2-yl)morpholine; 4-(5-Bromo-6-chloro-4-(trifluoromethyl)pyridin-2-yl)morpholine; Morpholine, 4-[5-bromo-6-chloro-4-(trifluoromethyl)-2-pyridinyl]-; 1053659-46-3; 5-Bromo-6-chloro-4-(trifluoromethyl)-2-morpholinopyridine; 2-Morpholino-5-bromo-6-chloro-4-(trifluoromethyl)pyridine |
| EINECS | Contact for details |
Quality Control
Our 4'-(5-Bromo-6-Chloro-4-(Trifluoromethyl)-Pyridin-2-Yl)Morpholine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity building blocks.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% (Area %) |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.





