Description

3-Bromo-6-Chloropicolinonitrile, 97% is a high-purity halogenated picolinonitrile derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex heterocyclic scaffolds, enabling the development of novel active ingredients. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials.
• Chemical Biology: Utilized in the creation of molecular probes and activity-based protein profiling (ABPP) reagents.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromo and chloro substituents.
• Library Synthesis: A valuable starting material for generating diverse compound libraries in high-throughput screening (HTS) campaigns.

Basic Information

Item	Details
Product Name	3-Bromo-6-Chloropicolinonitrile, 97%
CAS No.	1053659-39-4
Molecular Formula	C6H2BrClN2
Molecular Weight	217.45 g/mol
Synonyms	3-Bromo-6-chloro-2-cyanopyridine; 6-Chloro-3-bromopicolinonitrile; 2-Cyano-3-bromo-6-chloropyridine; 3-Bromo-6-chloropyridine-2-carbonitrile; Picolinonitrile, 3-bromo-6-chloro-; (3-Bromo-6-chloro-2-pyridyl)carbonitrile; 1053659-39-4
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Chloropicolinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.