Description

3-Chloro-2-(4-Iodophenoxy)-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, combining a pyridine core with halogenated and trifluoromethyl substituents, which is critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for targets requiring halogen-bonding or lipophilicity modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl and halogen groups enhance bioactivity and environmental stability.
• Material Science: Employed in the creation of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, aromatic structure.
• Chemical Biology: Acts as a versatile scaffold for designing molecular probes, enzyme inhibitors, or labeled compounds for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical building block for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	3-Chloro-2-(4-Iodophenoxy)-5-(Trifluoromethyl)Pyridine
CAS No.	1053658-85-7
Molecular Formula	C12H6ClF3INO
Molecular Weight	399.53 g/mol
Synonyms	3-Chloro-2-(4-iodophenoxy)-5-(trifluoromethyl)pyridine; 2-(4-Iodophenoxy)-3-chloro-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-3-chloro-2-(4-iodophenoxy)pyridine; Pyridine, 3-chloro-2-(4-iodophenoxy)-5-(trifluoromethyl)-; CAS 1053658-85-7
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-(4-Iodophenoxy)-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Every lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all test results are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.