Description

n-Methyl-n-(6-Morpholin-4'-Yl-3-Nitro-4-(Trifluoromethyl)Pyridin-2-Yl)Hydrazine CAS NO 1053658-19-7 is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine-hydrazine-morpholine hybrid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation drugs, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging its nitro and trifluoromethyl functional groups.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme inhibition and receptor binding.
• Material Science: Potential intermediate for the synthesis of specialty polymers and ligands for catalytic systems.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.

Basic Information

Product Name	n-Methyl-n-(6-Morpholin-4'-Yl-3-Nitro-4-(Trifluoromethyl)Pyridin-2-Yl)Hydrazine
CAS No.	1053658-19-7
Molecular Formula	C12H14F3N5O3
Molecular Weight	333.27 g/mol
Synonyms	2-Hydrazinyl-N-methyl-N-[6-(morpholin-4-yl)-3-nitro-4-(trifluoromethyl)pyridin-2-yl]acetamide; 1053658-19-7; N-Methyl-N-(6-morpholino-3-nitro-4-(trifluoromethyl)pyridin-2-yl)hydrazine; Methyl(6-morpholino-3-nitro-4-(trifluoromethyl)pyridin-2-yl)hydrazine; 2-(Methylhydrazinyl)-6-morpholino-3-nitro-4-(trifluoromethyl)pyridine; N-Methyl-N-[6-(4-morpholinyl)-3-nitro-4-(trifluoromethyl)-2-pyridinyl]hydrazine
EINECS	Contact for details

Quality Control

Our n-Methyl-n-(6-Morpholin-4'-Yl-3-Nitro-4-(Trifluoromethyl)Pyridin-2-Yl)Hydrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.