Description

2-Chloro-6-Pyrrolidin-1'-Yl-4-(Trifluoromethyl)-Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a halogenated pyridine core with a pyrrolidine substituent and a trifluoromethyl group, offering versatile reactivity for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• As a key pharmaceutical intermediate in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Utilized as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Employed in the research and development of agrochemicals, such as herbicides and insecticides, leveraging the biological activity of the pyridine scaffold.
• Serves as a precursor for the synthesis of ligands and catalysts used in metal-organic chemistry and cross-coupling reactions.
• Used in material science research for the development of advanced organic electronic materials and liquid crystals.

Basic Information

Product Name	2-Chloro-6-Pyrrolidin-1'-Yl-4-(Trifluoromethyl)-Pyridine
CAS No.	1053657-79-6
Molecular Formula	C10H10ClF3N2
Molecular Weight	250.65 g/mol
Synonyms	2-Chloro-6-(pyrrolidin-1-yl)-4-(trifluoromethyl)pyridine; 1-(6-Chloro-4-(trifluoromethyl)pyridin-2-yl)pyrrolidine; 2-Chloro-6-pyrrolidin-1-yl-4-trifluoromethylpyridine; 1053657-79-6; Pyrrolidine, 1-[6-chloro-4-(trifluoromethyl)-2-pyridinyl]-; 2-Chloro-6-(1-pyrrolidinyl)-4-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Pyrrolidin-1'-Yl-4-(Trifluoromethyl)-Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.