Description

2-(5-Chloromethyl-1H-Imidazol-2-Yl)Pyridine is a versatile heterocyclic building block with a reactive chloromethyl group, making it a critical intermediate in advanced organic synthesis. Its molecular architecture is specifically designed to facilitate the construction of complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and ligands.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, anti-cancer agents, and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds.
• Ligand & Catalyst Development: Serves as a foundational structure for creating chelating ligands in coordination chemistry and catalysis.
• Material Science Research: Building block for the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-(5-Chloromethyl-1H-Imidazol-2-Yl)Pyridine
CAS No.	1053657-25-2
Molecular Formula	C9H8ClN3
Molecular Weight	193.63 g/mol
Synonyms	2-(5-(Chloromethyl)-1H-imidazol-2-yl)pyridine; 2-(5-Chloromethylimidazol-2-yl)pyridine; Pyridine, 2-(5-(chloromethyl)-1H-imidazol-2-yl)-; 1H-Imidazole-2-methanol, 5-(2-pyridinyl)-, chloride; 5-(2-Pyridinyl)-1H-imidazole-2-methanol chloride
EINECS	Contact for details

Quality Control

Our 2-(5-Chloromethyl-1H-Imidazol-2-Yl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC and NMR data for each lot. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.