Description

tert-Butyl 4-(2-Chloropyridin-3-yl)piperidine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate (API intermediate) of significant importance in modern organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic architectures. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the synthesis of drug candidates, agrochemicals, and other specialty organic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides with specific activity profiles.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Ligand & Catalyst Development: Serves as a scaffold for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Potential monomer or precursor for functional polymers and advanced organic materials.

Basic Information

Product Name	tert-Butyl 4-(2-Chloropyridin-3-yl)piperidine-1-carboxylate
CAS No.	1053657-09-2
Molecular Formula	C15H21ClN2O2
Molecular Weight	296.79 g/mol
Synonyms	1-Boc-4-(2-chloropyridin-3-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(2-chloro-3-pyridinyl)piperidine; 4-(2-Chloro-3-pyridinyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(2-chloro-3-pyridinyl)-1-piperidinecarboxylate; 1-Boc-4-(2-chloro-3-pyridyl)piperidine; 4-(2-Chloropyridin-3-yl)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-(2-chloropyridin-3-yl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Chloropyridin-3-yl)piperidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.