Description

Ethyl 5-Piperazin-1-Ylmethylisoxazole-3-Carboxylate is a high-purity, heterocyclic organic compound featuring a piperazine-substituted isoxazole core, serving as a critical building block in advanced pharmaceutical synthesis. Its molecular architecture makes it a valuable intermediate for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology-related drug discovery programs. This compound is essential for medicinal chemists and R&D departments in pharmaceutical and biotechnology companies seeking to develop new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening (HTS) for new drug discovery.
• Active Pharmaceutical Ingredient (API) Development: Serves in the developmental pathway for novel APIs, where the piperazine and isoxazole motifs are pharmacologically significant.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic & Institutional Research: Utilized in university and research institute laboratories for studying structure-activity relationships (SAR) and biochemical pathways.

Basic Information

Product Name	Ethyl 5-Piperazin-1-Ylmethylisoxazole-3-Carboxylate
CAS No.	1053656-18-0
Molecular Formula	C12H19N3O3
Molecular Weight	253.30 g/mol
Synonyms	Ethyl 5-[(piperazin-1-yl)methyl]isoxazole-3-carboxylate; 5-(Piperazin-1-ylmethyl)isoxazole-3-carboxylic acid ethyl ester; 3-Isoxazolecarboxylic acid, 5-[(1-piperazinyl)methyl]-, ethyl ester; Ethyl 5-(piperazin-1-ylmethyl)-1,2-oxazole-3-carboxylate; 1053656-18-0; UNII-9F6I8J4Q5F; 9F6I8J4Q5F
EINECS	Contact for details

Quality Control

Our Ethyl 5-Piperazin-1-Ylmethylisoxazole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.