Description

6-Bromo-3-Fluoropyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromo and fluoro substituents for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized pyridine derivatives for advanced polymers, liquid crystals, and electronic materials.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	6-Bromo-3-Fluoropyridine-2-Carboxylic Acid
CAS No.	1052714-48-3
Molecular Formula	C6H3BrFNO2
Molecular Weight	220.00 g/mol
Synonyms	2-Bromo-5-fluoropyridine-3-carboxylic acid; 3-Fluoro-6-bromopicolinic acid; 6-Bromo-3-fluoropicolinic acid; 2-Carboxy-6-bromo-3-fluoropyridine; 1052714-48-3; 6-Bromo-3-fluoro-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Fluoropyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (High Purity Grades Available)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.