Description

6-Bromo-5-Fluoro-2-Pyridinecarboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. This compound matters as a key intermediate for introducing both bromo and fluoro substituents onto a pyridine scaffold, enabling the development of novel molecules with tailored properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating active ingredients, as well as by specialty chemical manufacturers producing advanced materials and ligands for catalysis.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated pyridine derivatives.
• Ligand Synthesis: Serves as a precursor for creating sophisticated ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Employed in the development of advanced organic electronic materials and liquid crystals due to its functionalized aromatic structure.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific halogenated pyridine motifs.

Basic Information

Product Name	6-Bromo-5-Fluoro-2-Pyridinecarboxylic Acid
CAS No.	1052714-46-1
Molecular Formula	C6H3BrFNO2
Molecular Weight	220.00 g/mol
Synonyms	5-Fluoro-6-bromopicolinic acid; 2-Pyridinecarboxylic acid, 6-bromo-5-fluoro-; 6-Bromo-5-fluoropyridine-2-carboxylic acid; 6-Bromo-5-fluoro-2-picolinic acid; 6-Bromo-5-fluoropicolinic acid; 5-Fluoro-6-bromopyridine-2-carboxylic acid; 2-Carboxy-6-bromo-5-fluoropyridine; 6-Br-5-F-2-PyCOOH
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Fluoro-2-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.