Description

3-Amino-6-Bromo-5-Fluoro-2-Pyridinecarboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is specifically engineered to serve as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its aromatic and carboxylic acid functionalities.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	3-Amino-6-Bromo-5-Fluoro-2-Pyridinecarboxylic Acid
CAS No.	1052714-14-3
Molecular Formula	C6H4BrFN2O2
Molecular Weight	235.01 g/mol
Synonyms	6-Bromo-5-fluoro-3-aminopicolinic acid; 3-Amino-6-bromo-5-fluoropyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 3-amino-6-bromo-5-fluoro-; 5-Fluoro-6-bromo-3-aminopicolinic acid; 6-Bromo-5-fluoro-3-amino-2-pyridinecarboxylic acid; 3-Amino-6-bromo-5-fluoro-2-carboxypyridine; 1052714-14-3
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Bromo-5-Fluoro-2-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.