Description

Ethanone, 1-[5-Bromo-1-[(4-Methylphenyl)Sulfonyl]-1H-Pyrrolo[2,3-B]Pyridin-3-Yl]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, especially those targeting kinase inhibition and other critical pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, particularly in oncology and antiviral research.
• Kinase Inhibitor Development: Used in the research and development of small-molecule kinase inhibitors due to its privileged pyrrolopyridine scaffold.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Ethanone, 1-[5-Bromo-1-[(4-Methylphenyl)Sulfonyl]-1H-Pyrrolo[2,3-B]Pyridin-3-Yl]-
CAS No.	1052633-38-1
Molecular Formula	C₁₇H₁₃BrN₂O₃S
Molecular Weight	405.27 g/mol
Synonyms	1-(5-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone; 3-Acetyl-5-bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl methyl ketone; 1-[5-Bromo-1-(4-methylphenyl)sulfonyl-pyrrolo[2,3-b]pyridin-3-yl]ethanone; 1052633-38-1; Tosyl-protected bromo pyrrolopyridine ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[5-Bromo-1-[(4-Methylphenyl)Sulfonyl]-1H-Pyrrolo[2,3-B]Pyridin-3-Yl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles where applicable, supporting our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.