Description

2-(5-Fluoro-2-Pyridin-4-Yl-1H-Indol-3-Yl)-Ethylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Biochemical Tool Compound: Serves as a precursor or reference standard in the development of enzyme inhibitors or receptor modulators.
• Preclinical Development: Employed in the scale-up synthesis of active pharmaceutical ingredients (APIs) for toxicology and early-phase clinical studies.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-(5-Fluoro-2-Pyridin-4-Yl-1H-Indol-3-Yl)-Ethylamine Hydrochloride
CAS No.	1052411-35-4
Molecular Formula	C16H15FN3·HCl
Molecular Weight	305.77 g/mol (Free base: 268.31 g/mol)
Synonyms	5-Fluoro-2-(4-pyridinyl)-1H-indole-3-ethanamine hydrochloride; 2-(5-Fluoro-2-(pyridin-4-yl)-1H-indol-3-yl)ethan-1-amine hydrochloride; 4-[3-(2-Aminoethyl)-5-fluoro-1H-indol-2-yl]pyridine hydrochloride; 1052411-35-4; 2-(5-Fluoro-2-(4-pyridyl)-1H-indol-3-yl)ethylamine HCl
EINECS	Contact for details

Quality Control

Our 2-(5-Fluoro-2-Pyridin-4-Yl-1H-Indol-3-Yl)-Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.