Description

5-Bromo-4-Hydroxynicotinic Acid is a halogenated derivative of nicotinic acid, serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both bromine and hydroxyl substituents on the pyridine ring, makes it a critical building block for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with specific modes of action.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate for creating functionalized polymers and advanced organic electronic materials.
• Chemical Biology: Useful as a probe or tag in biochemical research due to its reactive bromine moiety.
• Academic & R&D: Serves as a standard or starting material in university and corporate research laboratories for methodological studies.

Basic Information

Product Name	5-Bromo-4-Hydroxynicotinic Acid
CAS No.	1052114-83-6
Molecular Formula	C6H4BrNO3
Molecular Weight	218.01 g/mol
Synonyms	4-Hydroxy-5-bromonicotinic acid; 5-Bromo-4-hydroxypyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-bromo-4-hydroxy-; 5-Bromo-4-hydroxy-3-pyridinecarboxylic acid; 1052114-83-6; 4-Hydroxy-5-bromo-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Hydroxynicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥97.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.