Description

n-(2-Chloro-Pyridin-3-Yl)-2,3-Difluoro-Benzamide is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular frameworks. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development of new agrochemicals and drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Research: Serves as a foundational scaffold for developing new generation pesticides and herbicides, leveraging its difluoro and chloropyridine motifs for bioactivity.
• Chemical Synthesis Building Block: Used in organic and medicinal chemistry for constructing more complex heterocyclic compounds via cross-coupling and amidation reactions.
• Material Science Research: Potential application in the development of specialty chemicals and functional materials due to its unique electronic properties.

Basic Information

Item	Detail
Product Name	n-(2-Chloro-Pyridin-3-Yl)-2,3-Difluoro-Benzamide
CAS No.	1052103-20-4
Molecular Formula	C12H7ClF2N2O
Molecular Weight	268.65 g/mol
Synonyms	2,3-Difluoro-N-(2-chloropyridin-3-yl)benzamide; 2-Chloro-3-[(2,3-difluorobenzoyl)amino]pyridine; N-(2-Chloro-3-pyridinyl)-2,3-difluorobenzamide; 1052103-20-4; Benzamide, N-(2-chloro-3-pyridinyl)-2,3-difluoro-; AKOS025147065; 2,3-Difluoro-N-(2-chloro-3-pyridyl)benzamide
EINECS	Contact for details

Quality Control

Our n-(2-Chloro-Pyridin-3-Yl)-2,3-Difluoro-Benzamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.