Description

3-Bromo-5-Nitro-2-(2,2,2-Trifluoro-Ethoxy)-Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters because its unique structure, featuring bromo, nitro, and trifluoroethoxy substituents, provides distinct reactivity for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, ligand design, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogen and nitro groups for derivatization.
• Ligand and Catalyst Development: The pyridine core and substituents make it a valuable scaffold for designing novel ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, or organic electronic materials where fluorine and nitrogen-containing heterocycles are required.
• Chemical Biology Probes: Acts as a versatile building block for creating molecular probes and tags used in biochemical and cellular studies.

Basic Information

Product Name	3-Bromo-5-Nitro-2-(2,2,2-Trifluoro-Ethoxy)-Pyridine
CAS No.	1051372-09-8
Molecular Formula	C7H4BrF3N2O3
Molecular Weight	301.02 g/mol
Synonyms	2-(2,2,2-Trifluoroethoxy)-3-bromo-5-nitropyridine; 3-Bromo-5-nitro-2-(2,2,2-trifluoroethoxy)pyridine; Pyridine, 3-bromo-5-nitro-2-(2,2,2-trifluoroethoxy)-; 1051372-09-8
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Nitro-2-(2,2,2-Trifluoro-Ethoxy)-Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures material integrity for your most demanding research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.