Description

2-Bromo-6-Chloropyridin-3-Amine is a halogenated pyridine derivative that serves as a versatile and high-value building block in advanced organic synthesis. Its molecular structure, featuring both bromine and chlorine substituents on the pyridine ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The bromine and chlorine atoms provide distinct sites for selective Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-6-Chloropyridin-3-Amine
CAS No.	1050501-88-6
Molecular Formula	C5H4BrClN2
Molecular Weight	207.46 g/mol
Synonyms	3-Amino-2-bromo-6-chloropyridine; 2-Bromo-6-chloro-3-pyridinamine; 6-Chloro-2-bromopyridin-3-amine; (2-Bromo-6-chloropyridin-3-yl)amine; 2-Bromo-6-chloro-3-aminopyridine; 3-Pyridinamine, 2-bromo-6-chloro-; 2-Bromo-6-chloro-3-pyridylamine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Chloropyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.