Description

1-Benzyl 4-Methyl 2-(tert-Butoxycarbonyl)Succinate is a high-purity, protected succinate derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in the orthogonal protection of carboxylic acid and hydroxyl groups, enabling precise, multi-step reactions in complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, especially those requiring chiral centers.
• Peptidomimetics & Protease Inhibitor Synthesis: Used in constructing backbone structures that mimic peptides for therapeutic applications.
• Asymmetric Synthesis: Serves as a chiral precursor or auxiliary in stereoselective reactions to produce enantiomerically pure compounds.
• Fine Chemical & Specialty Chemical Production: Intermediate in the manufacture of advanced agrochemicals, flavors, and fragrances.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke production runs where specific protected intermediates are required.

Basic Information

Product Name	1-Benzyl 4-Methyl 2-(tert-Butoxycarbonyl)Succinate
CAS No.	1050238-07-7
Molecular Formula	C18H24O6
Molecular Weight	336.38 g/mol
Synonyms	2-(tert-Butoxycarbonyl)butanedioic acid 1-benzyl 4-methyl ester; 1-Benzyl 4-methyl 2-((tert-butoxy)carbonyl)succinate; Succinic acid, 2-[(1,1-dimethylethoxy)carbonyl]-, 1-benzyl 4-methyl ester; Benzyl methyl 2-(tert-butoxycarbonyl)succinate; Boc-Asp(OBzl)-OMe; Methyl benzyl 2-(Boc)succinate; (2S)-1-Benzyl 4-methyl 2-[(tert-butoxy)carbonyl]butanedioate (for enantiomer); Protected aspartic acid derivative
EINECS	Contact for details

Quality Control

Our 1-Benzyl 4-Methyl 2-(tert-Butoxycarbonyl)Succinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomer-specific grades available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.