Description

2-Hydrazino-5-(Trifluoromethyl)Pyridine Hydrochloride is a high-purity, functionalized pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the hydrazine moiety combined with the electron-withdrawing trifluoromethyl group, enabling the construction of complex heterocyclic scaffolds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine-hydrazine structure.
• Material Science Research: Serves as a building block for creating specialized ligands, catalysts, and functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Heterocyclic Chemistry: A versatile reagent for constructing complex nitrogen-containing heterocycles like pyrazoles and triazoles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects and process development.

Basic Information

Product Name	2-Hydrazino-5-(Trifluoromethyl)Pyridine Hydrochloride
CAS No.	1049744-89-9
Molecular Formula	C6H7ClF3N3
Molecular Weight	225.59 g/mol
Synonyms	5-(Trifluoromethyl)pyridine-2-hydrazine hydrochloride; 2-Hydrazinyl-5-(trifluoromethyl)pyridine hydrochloride; 5-(Trifluoromethyl)-2-hydrazinopyridine hydrochloride; 2-Hydrazino-5-trifluoromethylpyridine HCl; (5-Trifluoromethyl-2-pyridyl)hydrazine hydrochloride; 2-Pyridinylhydrazine, 5-(trifluoromethyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Hydrazino-5-(Trifluoromethyl)Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.