Description

(+/-)-trans-4-(2-Pyridinyl)Pyrrolidine-3-Carboxylic Acid Dihydrochloride is a high-purity, pharmaceutically relevant chiral building block and intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry for drug discovery and development. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in creating novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents.
• Medicinal Chemistry Research: Used as a building block for constructing complex molecular scaffolds in drug discovery programs.
• Ligand Synthesis: Serves as a precursor for the development of novel ligands in catalysis and chemical biology.
• Chemical Biology Probes: Utilized in the synthesis of probes for studying biological pathways and target engagement.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).
• Academic Research: Used in university and institutional labs for synthetic organic chemistry and methodology development.

Basic Information

Product Name	(+/-)-trans-4-(2-Pyridinyl)Pyrrolidine-3-Carboxylic Acid Dihydrochloride
CAS No.	1049739-70-9
Molecular Formula	C10H14N2O2 • 2HCl
Molecular Weight	279.16 g/mol (free base: 194.23 g/mol)
Synonyms	trans-4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid dihydrochloride; 4-(2-Pyridyl)-3-pyrrolidinecarboxylic acid dihydrochloride (racemic trans); 3-Pyrrolidinecarboxylic acid, 4-(2-pyridinyl)-, hydrochloride (1:2), trans-(±)-; 4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid hydrochloride (trans racemate); (3R*,4S*)-4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid dihydrochloride; (3S*,4R*)-4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid dihydrochloride; 1049739-70-9; 2-Pyridylpyrrolidine-3-carboxylic acid dihydrochloride (trans racemic)
EINECS	Contact for details

Quality Control

Our (+/-)-trans-4-(2-Pyridinyl)Pyrrolidine-3-Carboxylic Acid Dihydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.