Description

tert-Butyl 4,5-Dimethoxypyridin-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine-based structure with protective carbamate and methoxy functional groups. This compound matters as a critical building block in modern organic synthesis, enabling the development of complex molecules with high precision and yield. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly within medicinal chemistry and process research.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, especially those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to modify pharmacokinetic properties.
• Process Chemistry Development: Serves as a standardized starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Employed in methodological studies for constructing heterocyclic compounds and investigating new catalytic reactions.
• Custom Synthesis: A foundational component for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	tert-Butyl 4,5-Dimethoxypyridin-3-Ylcarbamate
CAS No.	1049677-55-5
Molecular Formula	C12H18N2O4
Molecular Weight	254.28 g/mol
Synonyms	3-(((tert-Butoxy)carbonyl)amino)-4,5-dimethoxypyridine; 4,5-Dimethoxy-3-pyridinylcarbamic acid 1,1-dimethylethyl ester; tert-Butyl N-(4,5-dimethoxypyridin-3-yl)carbamate; BOC-4,5-Dimethoxypyridin-3-amine; 3-(Boc-amino)-4,5-dimethoxypyridine; tert-Butyl (4,5-dimethoxy-3-pyridinyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4,5-Dimethoxypyridin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with ICH guidelines, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.