Description

tert-Butyl 4-Formyl-5-Methoxypyridin-3-Ylcarbamate is a high-purity, functionalized pyridine derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic combination of a protected amine (carbamate) and an aldehyde functional group, enabling precise and controlled chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the pyridine core is a common structural motif.
• Chemical Research & Development: Serves as a versatile precursor for creating libraries of compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand and Catalyst Development: The aldehyde and protected amine groups make it suitable for constructing complex chelating ligands and organocatalysts.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers or organic electronic materials requiring specific pyridine-based monomers.

Basic Information

Product Name	tert-Butyl 4-Formyl-5-Methoxypyridin-3-Ylcarbamate
CAS No.	1049677-54-4
Molecular Formula	C12H16N2O4
Molecular Weight	252.27 g/mol
Synonyms	tert-Butyl (4-formyl-5-methoxypyridin-3-yl)carbamate; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-methoxy-4-pyridinecarboxaldehyde; 5-Methoxy-4-formylpyridin-3-yl-carbamic acid tert-butyl ester; tert-Butyl N-(4-formyl-5-methoxypyridin-3-yl)carbamate; 3-(tert-Butoxycarbonylamino)-5-methoxyisonicotinaldehyde; BOC-3-Amino-5-methoxy-4-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Formyl-5-Methoxypyridin-3-Ylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent oxidation and moisture uptake. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.