Description

2-Chloro-3-Methyl-1,5-Naphthyridine is a high-purity, synthetically versatile naphthyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated and methylated structure, which provides distinct reactivity for constructing complex heterocyclic systems. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting kinase inhibition or other biological pathways where the naphthyridine scaffold is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers, ligands for catalysis, or organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce the naphthyridine moiety into more complex molecules.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic routes in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Chloro-3-Methyl-1,5-Naphthyridine
CAS No.	1049030-27-4
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	2-Chloro-3-methyl-1,5-naphthyridine; 1,5-Naphthyridine, 2-chloro-3-methyl-; 3-Methyl-2-chloro-1,5-naphthyridine; 2-Chloro-3-methyl-[1,5]naphthyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Methyl-1,5-Naphthyridine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.