Description

4-(n-Boc-Aminomethyl)-2-Bromopyridine is a high-purity, protected amine building block essential for modern organic synthesis. This compound is specifically designed to facilitate the controlled introduction of an aminomethylpyridine moiety into complex molecular architectures, offering a critical handle for further functionalization. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), ligands, and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Ligand Synthesis: Used to construct sophisticated chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a building block for creating new active ingredients with potential herbicidal or insecticidal properties.
• Peptide Mimetics: Incorporated into peptide backbones to enhance stability, bioavailability, or to introduce specific binding motifs.
• Chemical Biology Probes: Enables the creation of tagged molecules for studying biological pathways and target engagement.
• Material Science: A precursor for functionalized polymers and advanced organic materials with tailored properties.

Basic Information

Product Name	4-(n-Boc-Aminomethyl)-2-Bromopyridine
CAS No.	1049025-21-9
Molecular Formula	C12H17BrN2O2
Molecular Weight	301.18 g/mol
Synonyms	2-Bromo-4-((tert-butoxycarbonylamino)methyl)pyridine; 4-((tert-Butoxycarbonylamino)methyl)-2-bromopyridine; 2-Bromo-4-((Boc-amino)methyl)pyridine; tert-Butyl N-[(2-bromopyridin-4-yl)methyl]carbamate; Boc-AM(2-Br-4-Py); N-Boc-4-Aminomethyl-2-bromopyridine; 4-(Boc-aminomethyl)-2-bromopyridine; 1049025-21-9
EINECS	Contact for details

Quality Control

Our 4-(n-Boc-Aminomethyl)-2-Bromopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.