Description

1-Cyclohexyl-1-Tosylmethyl Isocyanide is a specialized organic building block featuring both an isocyanide functional group and a tosyl-protected methylene unit. This compound is valued for its versatility as a key intermediate in multi-component reactions, enabling the efficient synthesis of complex heterocyclic scaffolds and pharmacophores. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular libraries and active ingredients.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of nitrogen-containing heterocycles via Passerini and Ugi multi-component reactions for drug discovery.
• Agrochemical Research: Used to build novel pesticidal and herbicidal compounds with complex ring systems.
• Material Science: Serves as a precursor for functionalized polymers and ligands with tailored properties.
• Academic & R&D: Employed in methodological studies to develop new synthetic routes and catalytic processes.
• Chemical Biology: Utilized as a probe or linker in bioconjugation chemistry due to the reactive isocyanide group.

Basic Information

Product Name	1-Cyclohexyl-1-Tosylmethyl Isocyanide
CAS No.	1048971-67-0
Molecular Formula	C15H19NO2S
Molecular Weight	277.38 g/mol
Synonyms	1-Cyclohexyl-1-[(4-methylphenyl)sulfonyl]methyl isocyanide; 1-Cyclohexyl-1-(p-tolylsulfonyl)methyl isocyanide; 1-Isocyano-1-(p-toluenesulfonylmethyl)cyclohexane; 1-Cyclohexyl-1-(tosylmethyl)isocyanide; Tosylmethyl isocyanide cyclohexyl derivative; TOSMIC cyclohexyl derivative; (Isocyanocyclohexyl)methyl p-tolyl sulfone
EINECS	Contact for details

Quality Control

Our 1-Cyclohexyl-1-Tosylmethyl Isocyanide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced intermediates used in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.