Description

1-Cyclopentyl-1-Tosylmethyl Isocyanide is a specialized organic building block featuring a unique combination of a cyclopentyl group, a tosyl-protected methylene unit, and a highly reactive isocyanide functional group. This compound matters for its versatility as a key intermediate in multi-component reactions, enabling the efficient synthesis of complex heterocyclic scaffolds and natural product analogs. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular libraries and active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly for creating heterocyclic cores via Passerini and Ugi multi-component reactions.
• Agrochemical Research: Used in the development of novel pesticides and herbicides by providing a versatile scaffold for structure-activity relationship (SAR) studies.
• Material Science: Serves as a building block for advanced organic materials and functional polymers requiring specific isocyanide-derived linkages.
• Academic & Discovery Chemistry: Enables the exploration of new synthetic methodologies and the construction of diverse compound libraries for biological screening.
• Peptidomimetics Synthesis: Facilitates the creation of peptide analogs and constrained peptidomimetics for therapeutic applications.

Basic Information

Product Name	1-Cyclopentyl-1-Tosylmethyl Isocyanide
CAS No.	1048971-66-9
Molecular Formula	C14H17NO2S
Molecular Weight	263.36 g/mol
Synonyms	1-Cyclopentyl-1-[(4-methylphenyl)sulfonyl]methyl isocyanide; 1-Isocyano-1-[(p-tolylsulfonyl)methyl]cyclopentane; 1-Cyclopentyl-1-(p-toluenesulfonylmethyl) isocyanide; 1-Cyclopentyl-1-(tosylmethyl)isocyanide; 1-Cyclopentyl-1-(p-tolylsulfonylmethyl)isocyanide; 1-Cyclopentyl-1-(4-methylbenzenesulfonylmethyl)isocyanide; Tosylmethyl isocyanide cyclopentyl derivative
EINECS	Contact for details

Quality Control

Our 1-Cyclopentyl-1-Tosylmethyl Isocyanide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and degradation. Keep away from heat, sparks, and open flame. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.