Description

4-(Thiophen-2-Yl)Pyridin-3-Amine is a high-purity heterocyclic aromatic amine building block, valued for its unique molecular architecture that combines pyridine and thiophene moieties. This compound is essential for advanced research and development in medicinal chemistry, serving as a critical precursor for synthesizing novel pharmaceutical candidates and functional materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a building block for organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs) due to its electron-rich character.
• Ligand Synthesis: Employed in the preparation of novel chelating ligands for catalysis and metal complexation studies.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	4-(Thiophen-2-Yl)Pyridin-3-Amine
CAS No.	1048960-62-8
Molecular Formula	C9H8N2S
Molecular Weight	176.24 g/mol
Synonyms	3-Amino-4-(2-thienyl)pyridine; 4-(2-Thienyl)-3-pyridinamine; 4-(Thiophen-2-yl)pyridin-3-amine; 3-Pyridinamine, 4-(2-thienyl)-; 1048960-62-8; 4-(2-Thienyl)-3-aminopyridine; 4-(Thiophen-2-Yl)-3-Pyridinamine
EINECS	Contact for details

Quality Control

Every batch of 4-(Thiophen-2-Yl)Pyridin-3-Amine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.