Description

Lasofoxifene Sulfate is a selective estrogen receptor modulator (SERM) pharmaceutical compound. It is a critical active pharmaceutical ingredient (API) valued for its targeted therapeutic action in the treatment of postmenopausal osteoporosis and other estrogen-related conditions. This high-purity compound is essential for pharmaceutical manufacturers and research institutions engaged in the development and production of advanced hormone therapy medications.

Application

• Primary Active Pharmaceutical Ingredient (API) in solid oral dosage forms for osteoporosis treatment.
• Key intermediate in advanced pharmaceutical research for selective estrogen receptor modulators (SERMs).
• Reference standard for quality control and analytical method development in pharmaceutical laboratories.
• Biochemical research tool for studying estrogen receptor pathways and bone metabolism.
• Development of novel therapeutic formulations for breast cancer prevention and other hormone-dependent conditions.
• Manufacturing of clinical trial materials for investigational new drug (IND) applications.

Basic Information

Product Name	Lasofoxifene Sulfate
CAS No.	1048953-96-3
Molecular Formula	C₂₈H₂₈FNO₃ • H₂SO₄
Molecular Weight	539.60 g/mol
Synonyms	Lasofoxifene Sulphate; (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-yl 4-fluorophenyl sulfonate sulfate; CP-336,156; Fablyn (brand name); Fablyn Sulfate; Lasofoxifene Sulphate Salt; Lasofoxifene Hydrogen Sulfate
EINECS	Contact for details

Quality Control

Our Lasofoxifene Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmaceutical-grade specifications, including identity, purity, and impurity profile verification. Certificates of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters are provided and can be tailored to meet specific pharmacopeial (e.g., USP) or client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfate Content	Conforms to theoretical stoichiometry

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.