Description

3-Oxo-4-(3-Trifluoromethyl-Phenyl)-Butyric Acid Methyl Ester is a high-purity, versatile β-keto ester building block featuring a trifluoromethylphenyl substituent. This compound is valued for its role as a critical synthetic intermediate in advanced organic synthesis, particularly in the construction of complex heterocyclic and pharmaceutical scaffolds. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and fine chemical production.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science Research: Serves as a monomer or precursor for developing advanced polymers and functional materials with specific optical or electronic properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic research applications.
• Academic & Industrial R&D: A valuable reagent for methodology development in organic chemistry, including studies on cross-coupling reactions and asymmetric synthesis.

Basic Information

Product Name	3-Oxo-4-(3-Trifluoromethyl-Phenyl)-Butyric Acid Methyl Ester
CAS No.	1048918-10-0
Molecular Formula	C12H11F3O3
Molecular Weight	260.21 g/mol
Synonyms	Methyl 3-oxo-4-[3-(trifluoromethyl)phenyl]butanoate; Methyl 4-(3-Trifluoromethylphenyl)-3-oxobutyrate; 3-Oxo-4-(3-trifluoromethylphenyl)butyric acid methyl ester; 4-(3-(Trifluoromethyl)phenyl)-3-oxobutanoic acid methyl ester; β-Keto ester CF3-phenyl derivative; Butanoic acid, 3-oxo-4-[3-(trifluoromethyl)phenyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our 3-Oxo-4-(3-Trifluoromethyl-Phenyl)-Butyric Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.