Description

Ethyl 4-(3,4-Dichlorophenyl)-3-Oxobutanoate is a high-purity, versatile β-keto ester intermediate characterized by its dichlorophenyl functional group. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a key building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the dichlorophenyl moiety.
• Organic Synthesis & Research: Used in academic and industrial research laboratories for constructing complex molecular architectures via Claisen condensations and other C-C bond-forming reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring specific chlorinated aromatic structures.
• Process Chemistry & Scale-up: Supplied in development and commercial quantities to support process optimization and pilot plant campaigns for new chemical entities.

Basic Information

Product Name	Ethyl 4-(3,4-Dichlorophenyl)-3-Oxobutanoate
CAS No.	1048916-53-5
Molecular Formula	C12H12Cl2O3
Molecular Weight	275.13 g/mol
Synonyms	Ethyl 3-oxo-4-(3,4-dichlorophenyl)butanoate; 4-(3,4-Dichlorophenyl)-3-oxobutanoic Acid Ethyl Ester; Ethyl 4-(3,4-Dichlorophenyl)acetoacetate; 3-Oxo-4-(3,4-dichlorophenyl)butyric Acid Ethyl Ester; Butanoic acid, 4-(3,4-dichlorophenyl)-3-oxo-, ethyl ester; Ethyl (3,4-dichlorobenzyl)acetoacetate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(3,4-Dichlorophenyl)-3-Oxobutanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent batch-to-batch performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.