Description

5-Chloro-2-Hydroxynicotinonitrile is a versatile heterocyclic building block and key synthetic intermediate. Its molecular structure, featuring both chloro and hydroxynitrile substituents on a pyridine ring, makes it a valuable precursor for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its reactive nitrile and halogen sites.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating specialized ligands used in catalytic processes.
• Material Science Research: Acts as a monomer or precursor for synthesizing functional polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	5-Chloro-2-Hydroxynicotinonitrile
CAS No.	1048913-62-7
Molecular Formula	C6H3ClN2O
Molecular Weight	154.55 g/mol
Synonyms	5-Chloro-2-hydroxypyridine-3-carbonitrile; 2-Hydroxy-5-chloronicotinonitrile; 3-Cyano-5-chloro-2-pyridinol; 5-Chloro-2-oxo-1,2-dihydropyridine-3-carbonitrile; 5-Chloro-3-cyano-2-pyridone; 5-Chloro-2-pyridone-3-carbonitrile; 5-Chloro-2(1H)-pyridinone-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Hydroxynicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.