Description

Ethyl 2-(1H-Pyrrolo[2,3-B]Pyridin-1-Yl)Acetate is a high-purity, advanced pharmaceutical intermediate featuring a fused pyrrolopyridine core structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing innovative therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting specific biological pathways.
• Kinase Inhibitor Development: Used in the research and production of small molecule kinase inhibitors for cancer therapy.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Employed in the multi-step synthesis of final Active Pharmaceutical Ingredients (APIs) requiring the pyrrolo[2,3-b]pyridine moiety.
• Biochemical Tool Compound: Used in biochemical assays and as a reference standard in pharmacological research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Ethyl 2-(1H-Pyrrolo[2,3-B]Pyridin-1-Yl)Acetate
CAS No.	1048913-05-8
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridin-1-ylacetic Acid Ethyl Ester; Ethyl (1H-Pyrrolo[2,3-b]pyridin-1-yl)acetate; 1-Aza-7-deazaindole-1-acetic Acid Ethyl Ester; 7-Deazapurine-1-acetic Acid Ethyl Ester; 1H-Pyrrolo[2,3-b]pyridine-1-acetic Acid Ethyl Ester; Ethyl 2-(7-Azaindol-1-yl)acetate; 1-(Ethoxycarbonylmethyl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our Ethyl 2-(1H-Pyrrolo[2,3-B]Pyridin-1-Yl)Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.