Description

5-(3,4-Difluorophenyl)Pyridine-3-Carboxylic Acid is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a difluorophenyl moiety with a pyridine carboxylic acid group, enabling precise modifications in complex molecular frameworks. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers due to its conjugated system.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	5-(3,4-Difluorophenyl)Pyridine-3-Carboxylic Acid
CAS No.	1048486-16-3
Molecular Formula	C12H7F2NO2
Molecular Weight	235.19 g/mol
Synonyms	3-Pyridinecarboxylic acid, 5-(3,4-difluorophenyl)-; 5-(3,4-Difluorophenyl)nicotinic acid; 5-(3,4-Difluorophenyl)-3-pyridinecarboxylic acid; 1048486-16-3; Nicotinic acid, 5-(3,4-difluorophenyl)-; AI3-63500; ZINC000103079753
EINECS	Contact for details

Quality Control

Every batch of 5-(3,4-Difluorophenyl)Pyridine-3-Carboxylic Acid is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.