Description

1-Triethylsilyl-1-Heptyne, 95% is a high-purity organosilicon reagent featuring a terminal alkyne functionality protected by a triethylsilyl (TES) group. This compound is a critical building block in advanced organic synthesis, valued for its role as a stable, protected acetylene equivalent in cross-coupling reactions and metal-catalyzed transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Serves as a key building block in the synthesis of complex drug candidates, particularly in Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Development: Used in the research and production of novel pesticides and herbicides where the alkyne moiety is integral to biological activity.
• Material Science & Polymer Chemistry: Acts as a monomer or functionalizing agent in the creation of specialized polymers, dendrimers, and advanced materials with tailored properties.
• Organic Synthesis & Methodology Development: A versatile reagent for academic and industrial research in developing new synthetic methodologies, including click chemistry and cycloaddition reactions.
• Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric catalysis.
• Chemical Biology & Bioconjugation: Useful for labeling biomolecules or modifying surfaces via its reactive alkyne handle under mild conditions.

Basic Information

Product Name	1-Triethylsilyl-1-Heptyne, 95%
CAS No.	1047660-72-9
Molecular Formula	C₁₃H₂₆Si
Molecular Weight	210.43 g/mol
Synonyms	Hept-1-yn-1-yltriethylsilane; Triethyl(hept-1-yn-1-yl)silane; 1-Heptyne, 1-(triethylsilyl)-; TES-Protected 1-Heptyne; Triethylsilylheptyne; (Hept-1-yn-1-yl)triethylsilane; 1-(Triethylsilyl)hept-1-yne
EINECS	Contact for details

Quality Control

Our 1-Triethylsilyl-1-Heptyne, 95% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.