Description

3-(4-Fluorophenyl)-1-Oxa-3,8-Diazaspiro-[4.5]Decan-2-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and oxadiazine structure. This compound is critical for medicinal chemistry research and development, offering a versatile scaffold for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new drugs, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The spirocyclic oxadiazine core is valuable for designing inhibitors targeting specific enzymes.
• CNS Drug Candidates: Applied in the research and development of potential therapeutics for neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.

Basic Information

Product Name	3-(4-Fluorophenyl)-1-Oxa-3,8-Diazaspiro-[4.5]Decan-2-One
CAS No.	1047655-95-7
Molecular Formula	C14H16FN3O2
Molecular Weight	277.30 g/mol
Synonyms	1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 3-(4-fluorophenyl)-; 3-(p-Fluorophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one; 1-Oxa-3,8-diazaspiro[4.5]decane-2-one, 3-(4-fluorophenyl)-; 3-(4-Fluorophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one; Spiro[4.5]decan-2-one, 3-(4-fluorophenyl)-1-oxa-3,8-diaza-; CAS 1047655-95-7
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-1-Oxa-3,8-Diazaspiro-[4.5]Decan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring material suitable for advanced research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorinating agents. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.