Description

5H-Spiro[Furo[3,4-B]Pyridine-7,4'-Piperidine] Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new bioactive molecules.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and protein interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and pharmacology.
• Library Synthesis: A valuable component for creating diverse chemical libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	5H-Spiro[Furo[3,4-B]Pyridine-7,4'-Piperidine] Dihydrochloride
CAS No.	1047655-67-3
Molecular Formula	C11H15Cl2N2O
Molecular Weight	262.15 g/mol
Synonyms	5H-Spiro[furo[3,4-b]pyridine-7,4'-piperidine] dihydrochloride; 5H-Spiro[furo[3,4-b]pyridine-7,4'-piperidine] hydrochloride (1:2); 5H-Spiro[furo[3,4-b]pyridine-7,4'-piperidine] dihydrochloride salt; 1047655-67-3; 5H-Spiro[furo[3,4-b]pyridine-7,4'-piperidinium] dichloride; Spiro[furo[3,4-b]pyridine-7,4'-piperidine] dihydrochloride; 5H-Spiro[furo[3,4-b]pyridine-7,4'-piperidine] HCl salt.
EINECS	Contact for details

Quality Control

Our 5H-Spiro[Furo[3,4-B]Pyridine-7,4'-Piperidine] Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.