Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxamide, 5-Bromo-1-(Phenylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate (API) with the CAS registry number 1046793-69-4. This compound is a critical building block in modern medicinal chemistry, valued for its unique heterocyclic structure that enables the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop novel small-molecule therapeutics.
• Kinase Inhibitor Development: Its pyrrolopyridine scaffold is a privileged structure in the design of potent and selective kinase inhibitors for cancer treatment.
• CNS Drug Discovery: Employed in the research and development of compounds targeting neurological disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxamide, 5-Bromo-1-(Phenylsulfonyl)-
CAS No.	1046793-69-4
Molecular Formula	C14H10BrN3O3S
Molecular Weight	380.22 g/mol
Synonyms	5-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide; 5-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide; 1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, 5-bromo-1-(phenylsulfonyl)-; 1046793-69-4; 5-Bromo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxamide, 5-Bromo-1-(Phenylsulfonyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.