Description

Atorvastatin Lactam Phenanthrene Calcium Salt is a key pharmaceutical intermediate in the synthesis of atorvastatin, a leading statin medication. This high-purity compound is critical for ensuring the efficacy and safety of the final active pharmaceutical ingredient (API). It is primarily required by manufacturers in the pharmaceutical industry engaged in the research, development, and production of cardiovascular drugs.

Application

• Primary Intermediate in the multi-step synthesis of Atorvastatin Calcium, the active ingredient in cholesterol-lowering medications.
• Reference Standard for analytical method development and quality control (QC) testing in pharmaceutical laboratories.
• Process Research & Development (R&D) for optimizing synthetic routes and scaling up production of statin-based APIs.
• Active Pharmaceutical Ingredient (API) Manufacturing for producing finished dosage forms under Good Manufacturing Practice (GMP) conditions.
• Contract Manufacturing Organizations (CMOs) and generic drug producers requiring reliable, high-quality intermediates.

Basic Information

Product Name	Atorvastatin Lactam Phenanthrene Calcium Salt
CAS No.	1046378-58-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Atorvastatin Lactam Phenanthrene Calcium; Atorvastatin Calcium Salt Lactam Phenanthrene; Atorvastatin Impurity; Atorvastatin Related Compound; (3R,5R)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic Acid Calcium Salt Lactam Phenanthrene Derivative; Atorvastatin Intermediate; CAS 1046378-58-8
EINECS	Contact for details

Quality Control

Our Atorvastatin Lactam Phenanthrene Calcium Salt is manufactured under strict quality systems to meet the rigorous standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all test results is provided to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	Contact for details
Heavy Metals	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.