Description

(2E)-1-{[1,1-Biphenyl]-4-Yl}-3-(3-Chlorophenyl)Prop-2-En-1-One CAS NO 1046051-19-7 is a high-purity, synthetic chalcone derivative characterized by its specific (2E) stereochemistry and biphenyl-chlorophenyl structural motif. This compound matters as a critical advanced pharmaceutical intermediate and key building block in organic synthesis, enabling the development of novel active compounds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new molecules with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and central nervous system disorders.
• Organic Light-Emitting Diode (OLED) Material Research: Used as a core structure for developing new electron-transporting or host materials due to its conjugated system and molecular rigidity.
• Agrochemical Synthesis: Acts as a building block for creating new pesticides and herbicides, leveraging its bioactive chalcone scaffold.
• Chemical Biology Probe Development: Utilized in research to create molecular probes for studying enzyme function or protein interactions.
• Material Science: Investigated as a monomer or cross-linking agent for advanced polymers with specific optical or electronic properties.
• Academic & Industrial R&D: Employed in method development and discovery chemistry for constructing complex molecular architectures.

Basic Information

Product Name	(2E)-1-{[1,1-Biphenyl]-4-Yl}-3-(3-Chlorophenyl)Prop-2-En-1-One
CAS No.	1046051-19-7
Molecular Formula	C21H15ClO
Molecular Weight	318.80 g/mol
Synonyms	(E)-1-([1,1'-Biphenyl]-4-yl)-3-(3-chlorophenyl)prop-2-en-1-one; 3-Chloro-3'-phenylchalcone; (2E)-3-(3-Chlorophenyl)-1-(4-phenylphenyl)prop-2-en-1-one; 1-([1,1'-Biphenyl]-4-yl)-3-(3-chlorophenyl)-2-propen-1-one; (E)-3-(3-Chlorophenyl)-1-([1,1'-biphenyl]-4-yl)prop-2-en-1-one; Biphenyl-4-yl 3-chlorophenyl ketone (chalcone derivative); 1046051-19-7
EINECS	Contact for details

Quality Control

Our (2E)-1-{[1,1-Biphenyl]-4-Yl}-3-(3-Chlorophenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.