Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 5-Methoxy-, Ethyl Ester is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D teams and fine chemical manufacturers need this precise chemical scaffold to explore new therapeutic candidates and scale up production processes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various diseases.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials and functional dyes due to its conjugated π-system.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) exploring new chemical entities.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 5-Methoxy-, Ethyl Ester
CAS No.	1045856-81-2
Molecular Formula	C12H12N2O3
Molecular Weight	232.24 g/mol
Synonyms	Ethyl 5-Methoxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 5-Methoxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylic Acid Ethyl Ester; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-methoxy-, ethyl ester; 5-Methoxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylate ethyl ester; 1045856-81-2; Ethyl 5-methoxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 5-Methoxy-, Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for pharmaceutical applications, and specifications can be aligned with client requirements for advanced R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Any single unknown impurity	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.