Description

1H-Pyrrolo[3,2-B]Pyridine-6-Boronic Acid Pinacol Ester is a high-purity, heterocyclic boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecular architectures via palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients and advanced functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Serves as a precursor for creating organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Ligand & Catalyst Development: Utilized to synthesize novel bidentate or tridentate ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring the introduction of a functionalized pyrrolopyridine core.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine-6-Boronic Acid Pinacol Ester
CAS No.	1045855-91-1
Molecular Formula	C13H17BN2O2
Molecular Weight	244.10 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine-6-boronic acid pinacol ester; 6-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[3,2-b]pyridine; 6-Boronic acid pinacol ester-1H-pyrrolo[3,2-b]pyridine; Pyrrolo[3,2-b]pyridine-6-boronic acid pinacol ester; 1H-Pyrrolo[3,2-b]pyridin-6-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-B]Pyridine-6-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The container should be kept tightly sealed in a dry inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.