Description

4-Iodo-5-Methoxypyridin-3-Amine is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique halogenated and aminated structure, which provides versatile reactivity for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other heterocyclic-based therapeutics.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging its halogen and methoxy groups for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for organic electronic materials, such as charge-transport layers or photoactive components.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Biology Probes: Used to create labeled compounds or probes for studying biological pathways and mechanisms.

Basic Information

Item	Detail
Product Name	4-Iodo-5-Methoxypyridin-3-Amine
CAS No.	1045855-66-0
Molecular Formula	C6H7IN2O
Molecular Weight	250.04 g/mol
Synonyms	3-Amino-4-iodo-5-methoxypyridine; 5-Methoxy-4-iodopyridin-3-amine; 4-Iodo-5-methoxy-3-pyridinamine; 3-Pyridinamine, 4-iodo-5-methoxy-; 1045855-66-0; 4-Iodo-5-methoxypyridin-3-ylamine
EINECS	Contact for details

Quality Control

Our 4-Iodo-5-Methoxypyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.