Description

3-Amino-5-Methoxyisonicotinonitrile is a high-value, multi-functional heterocyclic nitrile building block. This compound matters for its role as a critical intermediate in the synthesis of complex pharmaceutical molecules and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel pyridine-based scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, receptor antagonists, and other bioactive molecules targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for studying enzyme mechanisms and cellular processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	3-Amino-5-Methoxyisonicotinonitrile
CAS No.	1045855-60-4
Molecular Formula	C7H7N3O
Molecular Weight	149.15 g/mol
Synonyms	5-Methoxy-3-amino-4-cyanopyridine; 3-Amino-5-methoxypyridine-4-carbonitrile; 4-Cyano-5-methoxy-3-aminopyridine; 5-Methoxy-4-cyano-3-aminopyridine; 3-Amino-5-methoxy-4-pyridinecarbonitrile; 3-Amino-5-methoxynicotinonitrile; 5-Methoxy-3-pyridinamine-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Methoxyisonicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.