Description

2-Oxa-6-Azaspiro[3.3]Heptane, 6-(Diphenylmethyl)- is a high-value, spirocyclic organic building block with significant utility in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique bicyclic structure introduces desirable conformational and pharmacokinetic properties. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging its spirocyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor or core structure for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	2-Oxa-6-Azaspiro[3.3]Heptane, 6-(Diphenylmethyl)-
CAS No.	1045709-00-9
Molecular Formula	C18H19NO
Molecular Weight	265.35 g/mol
Synonyms	6-(Diphenylmethyl)-2-oxa-6-azaspiro[3.3]heptane; 6-Benzhydryl-2-oxa-6-azaspiro[3.3]heptane; 2-Oxa-6-azaspiro[3.3]heptane, 6-(diphenylmethyl)-; 6-(Diphenylmethyl)-2-oxa-6-azaspiro[3.3]heptane; Spiro[3.3]heptane-6-carboxylic acid, 2-oxa-6-aza-, diphenylmethyl ester (related); 1045709-00-9; 6-(Benzhydryl)-2-oxa-6-azaspiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our 2-Oxa-6-Azaspiro[3.3]Heptane, 6-(Diphenylmethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.